What is calculated
The original HOMA-IR arithmetic index.
HOMA-IR Calculator
HOMA-IR value
Enter your values, then calculate to see a verified result.
Reference range
How this result is calculated
A clear calculation path based on your inputs.
Inputs usedReview the information used for this result.
Full calculation and sourcesOpen Full calculation and sources to review the formula, assumptions, boundaries, and evidence.
Versioned calculationFormula v1.0.1
Method
Multiply same-draw fasting insulin and glucose and divide by 405.
Important boundary
Assay and population differences prevent one universal diagnostic cutoff.
Use one fasting drawUse the labeled input and matching unit.
Measured or label valueApply the original equationThe calculator applies the stated equation.
Full precision firstAvoid universal cutoffsKeep the boundary beside the result.
Reference, not diagnosisInterpretation
is the calculated HOMA-IR value.
Both laboratory inputs remain visible.
Interpretation requires the laboratory and clinical context.
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Method and test recordFormula v1.0.1
- Recorded scope
- health-wellness-completion
- Publisher
- CalculatorGeek
- Recorded review date
- 2026-10-05
- Next source review
- 2027-04-05
- Definition fixtures
- 2 configured scenarios
- Published examples
- 2 shown below
Recorded method
Verify the 405 equation, same-draw requirements, and glucose unit parity.
These records describe the published model and reference tests. A test-case count is not a certification of every possible input or an independent specialist review. Editorial policy
Known limitations
- No universal diagnostic threshold is applied.
- Requires a valid fasting same-draw sample.
- Insulin assays are not fully standardized.
- Acute illness and medicines can affect results.
Method sources
Latest model update
2026-10-05 - Initial evidence-limited shared-system implementation with fixtures, original support content, and contextual links.
Reference inputs and expected results
Up to 12 examples from the configured definition fixtures are shown. Expected values use the stated output units; invalid inputs are intended to be rejected.
| Case | Inputs | Expected result |
|---|---|---|
| fasting reference | Fasting glucose: 90 mg/dL; Fasting insulin: 8 uIU/mL | HOMA-IR: 1.77777778; Fasting glucose equivalent: 4.994 mmol/L (allowed numeric tolerance: 0.002) |
| mmol glucose equivalence | Fasting glucose: 4.994 mmol/L; Fasting insulin: 8 uIU/mL | HOMA-IR: 1.7778 (allowed numeric tolerance: 0.002) |
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On this page
What the HOMA-IR Calculator calculates
Calculate the original HOMA-IR index from same-draw fasting glucose and insulin.
The calculator supplies the formula result but deliberately does not label insulin resistance from a universal cutoff.
Continue this workflow with the CDC Prediabetes Risk Test. Apply the official CDC screening score.
How to use the HOMA-IR Calculator
- Use fasting glucose and insulin from the same blood draw.
- Check the glucose unit.
- Enter the laboratory values.
- Interpret with the assay, population, and clinical context.
Continue with the QUICKI Calculator. Calculate a different research index from the same fasting inputs.
Formula, variables and calculation order
HOMA-IR = glucose mg/dL x insulin uIU/mL / 405.
Inputs are validated and normalized before calculation. Full precision is retained until the displayed result is rounded.
Cross-check a different part of the decision with the A1C Calculator. Translate A1C to estimated average glucose.
Worked example and boundary check
Worked example
90 mg/dL glucose and 8 uIU/mL insulin gives HOMA-IR 1.78.
Boundary check
Thresholds reported in studies are not interchangeable across populations and assays.
How to interpret the result
Use the number only as a research or clinician-supported index, not as a self-diagnosis.
- No universal diagnostic threshold is applied.
- Requires a valid fasting same-draw sample.
- Insulin assays are not fully standardized.
- Acute illness and medicines can affect results.
For a separate result with different assumptions, open the Blood Pressure Calculator. Keep blood-pressure classification separate.
Frequently asked questions
What HOMA-IR is normal?
There is no single universal cutoff suitable for every population and assay.
Can I use nonfasting values?
That changes the meaning of the original fasting model.
Can I enter mmol/L glucose?
Yes; it converts to the mg/dL form of the equation.
Does this diagnose insulin resistance?
No.
Primary sources and evidence limits
Sources were checked 2026-10-05. A reference value, conversion, or schedule estimate is not a diagnosis, prescription, individualized treatment target, or substitute for professional care.