What is calculated
The published clinical PhenoAge composite from nine biomarkers and chronological age.
PhenoAge Calculator
Levine PhenoAge
Enter your values, then calculate to see a verified result.
Reference range
How this result is calculated
A clear calculation path based on your inputs.
Inputs usedReview the information used for this result.
Full calculation and sourcesOpen Full calculation and sources to review the method, assumptions, boundaries, and evidence.
Versioned calculationFormula v1.0.0
Method
Apply the original linear predictor, mortality transform, and age transform.
Important boundary
Lab methods, acute illness, population differences, and clinical context can affect interpretation.
Enter same-context laboratory valuesUse the labeled field and matching unit.
Apply the published transformThe calculator applies the displayed method at full precision.
Compare without diagnosingKeep the stated boundary beside the result.
Interpretation
The primary value is the equation output, not literal cellular age.
The signed difference keeps chronological age beside the result.
Abnormal laboratory results require qualified clinical interpretation.
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Related calculators and resources
Method and test recordFormula v1.0.0
- Recorded scope
- health-evidence-completion
- Publisher
- CalculatorGeek
- Recorded review date
- 2026-10-05
- Next source review
- 2027-04-05
- Definition fixtures
- 1 configured scenarios
- Published examples
- 1 shown below
Recorded method
Compare every coefficient, CRP unit conversion, nonlinear transform, and independent oracle result with the original open paper.
These records describe the published model and reference tests. A test-case count is not a certification of every possible input or an independent specialist review. Editorial policy
Known limitations
- Not a diagnosis or lifespan forecast.
- Requires valid laboratory results and exact units.
- The original model population may not match every user.
- Acute illness and laboratory variation can move the result.
Method sources
Latest model update
2026-10-05 - Initial evidence-limited shared-system implementation with fixtures, original support content, and contextual links.
Reference inputs and expected results
Up to 12 examples from the configured definition fixtures are shown. Expected values use the stated output units; invalid inputs are intended to be rejected.
| Case | Inputs | Expected result |
|---|---|---|
| independent published-formula fixture | Chronological age: 50 years; Albumin: 42 g/L; Creatinine: 80 umol/L; Glucose: 5.5 mmol/L; C-reactive protein: 1 mg/L; Lymphocyte percentage: 30 percent; Mean cell volume: 90 value; Red-cell distribution width: 13 percent; Alkaline phosphatase: 70 value; White blood-cell count: 6 value | Linear predictor: -8.8699166179; mortality_score: 0.0273391894; Levine PhenoAge: 44.0900208 years; Difference from chronological age: -5.9099792 years (allowed numeric tolerance: 0.0001) |
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On this page
What the PhenoAge Calculator calculates
Calculate the original Levine clinical PhenoAge composite from chronological age and nine laboratory biomarkers.
The route implements one named published model rather than an invented lifestyle quiz.
Start with the Health calculators hub when a neighboring workflow better matches the question.
How to use the PhenoAge Calculator
- Use laboratory results from the same clinical context where possible.
- Match every unit exactly.
- Calculate the composite and signed age difference.
- Discuss abnormal source biomarkers independently of the composite.
Continue with the A1C Calculator. Convert A1C and estimated average glucose.
Formula, variables and calculation order
xb = -19.907 - 0.0336 albumin + 0.0095 creatinine + 0.1953 glucose + 0.0954 ln(CRP mg/dL) - 0.012 lymphocytes + 0.0268 MCV + 0.3306 RDW + 0.00188 ALP + 0.0554 WBC + 0.0804 age, followed by the published mortality and age transforms.
Inputs are validated and normalized before the calculation. Working precision is retained until display rounding.
For a separate method, open the Blood Pressure Calculator. Classify a measured blood-pressure pair.
Worked example and boundary check
Worked example
Age 50 with albumin 42 g/L, creatinine 80 umol/L, glucose 5.5 mmol/L, CRP 1 mg/L, lymphocytes 30%, MCV 90 fL, RDW 13%, ALP 70 U/L, and WBC 6 gives about 44.09 years.
Boundary check
CRP must be positive because the equation uses a natural logarithm.
How to interpret the result
A difference from chronological age is an association-based research summary; it is not proof of accelerated or reversed aging.
- Not a diagnosis or lifespan forecast.
- Requires valid laboratory results and exact units.
- The original model population may not match every user.
- Acute illness and laboratory variation can move the result.
Compare the result with the Cholesterol Ratio Calculator. Calculate common lipid ratios.
Frequently asked questions
Is PhenoAge my true biological age?
No; it is a model output.
Why must CRP be above zero?
The equation uses ln(CRP).
Can I enter results from different dates?
That weakens interpretability because the model assumes one clinical context.
Should I change medicine from this result?
No.
Primary sources and evidence limits
Sources and version-sensitive boundaries were checked 2026-10-05. The page does not replace diagnosis, prescribing, emergency care, or individualized professional judgment.