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eGFR Calculator (2021 CKD-EPI Creatinine)

Updated Oct 2026 Used 1 times
Calculation inputsEnter measured or label values and keep their units attached.
Select the coefficient required by the published 2021 equation.
This adult creatinine equation is limited here to age 18+.
Use an IDMS-standardized laboratory creatinine result.

Guest calculations stay on this device. Signed-in results sync privately.

Your result

Estimated GFR

Enter your values, then calculate to see a verified result.

Inputs usedReview the information used for this result.
Full calculation and sourcesOpen Full calculation and sources to review the formula, assumptions, boundaries, and evidence.

Versioned calculationFormula v1.0.1

Formula definitionUnit-normalized calculationFormula v1.0.1

What is calculated

Adult race-free 2021 CKD-EPI creatinine eGFR.

Method

Apply sex-specific k and alpha coefficients to standardized creatinine and age.

Important boundary

The estimate is indexed to 1.73 m² and is not measured GFR.

Result actions
1
Use laboratory creatinineUse the labeled input and matching unit.Measured or label value
2
Apply 2021 coefficientsThe calculator applies the stated equation.Full precision first
3
Keep CKD criteria separateKeep the boundary beside the result.Reference, not diagnosis

Interpretation

is the indexed adult estimate.

The equation inputs remain visible.

Do not diagnose CKD from one number.

Use this result

Method and test recordFormula v1.0.1
Recorded scope
health-wellness-completion
Publisher
CalculatorGeek
Recorded review date
2026-10-05
Next source review
2027-04-05
Definition fixtures
3 configured scenarios
Published examples
3 shown below

Recorded method

Verify all published coefficients, min/max branches, sex factors, age power, and creatinine units.

These records describe the published model and reference tests. A test-case count is not a certification of every possible input or an independent specialist review. Editorial policy

Known limitations

  • Adult creatinine-only equation.
  • Not measured GFR.
  • Creatinine is affected by muscle mass, diet, medicines, and acute change.
  • Does not determine CKD diagnosis, prognosis, monitoring, referral, or drug dose.

Method sources

Latest model update

2026-10-05 - Initial evidence-limited shared-system implementation with fixtures, original support content, and contextual links.

Reference inputs and expected results

Up to 12 examples from the configured definition fixtures are shown. Expected values use the stated output units; invalid inputs are intended to be rejected.

CaseInputsExpected result
female adult referenceEquation sex coefficient: female; Age: 50 number; Standardized serum creatinine: 1 mg/dLEstimated GFR: 68.6334967 mL/min/1.73 m² (allowed numeric tolerance: 0.02)
male adult referenceEquation sex coefficient: male; Age: 60 number; Standardized serum creatinine: 1.2 mg/dLEstimated GFR: 69.239 mL/min/1.73 m² (allowed numeric tolerance: 0.05)
micromole equivalenceEquation sex coefficient: female; Age: 50 number; Standardized serum creatinine: 88.4 umol/LEstimated GFR: 68.6334967 mL/min/1.73 m² (allowed numeric tolerance: 0.02)

Report an issue with this tool. Include the page URL, units, expected answer, and steps to reproduce. Do not include sensitive personal information.

On this page

What the eGFR Calculator (2021 CKD-EPI Creatinine) calculates

Calculate adult 2021 CKD-EPI creatinine eGFR from age, equation sex coefficient, and standardized serum creatinine.

The implementation is race-free, names the equation in the result, and preserves the distinction between indexed eGFR and measured kidney function.

How to use the eGFR Calculator (2021 CKD-EPI Creatinine)

  1. Use an IDMS-standardized laboratory creatinine.
  2. Select the coefficient used by the equation.
  3. Enter adult age.
  4. Review the estimate with trends, urine albumin, and clinical context.

Formula, variables and calculation order

eGFR = 142 x min(Scr/k,1)^alpha x max(Scr/k,1)^-1.200 x 0.9938^age x female factor.

Inputs are validated and normalized before calculation. Full precision is retained until the displayed result is rounded.

Worked example and boundary check

Worked example

For a 50-year-old using the female coefficient and creatinine 1.0 mg/dL, eGFR is about 69 mL/min/1.73 m².

Boundary check

This route does not calculate pediatric Schwartz, cystatin-C, creatinine-cystatin, or body-surface-area-adjusted drug-dosing values.

How to interpret the result

Use the estimate with a clinician and laboratory report. CKD requires persistent findings or other markers; G1/G2 alone do not establish CKD without kidney-damage evidence.

  • Adult creatinine-only equation.
  • Not measured GFR.
  • Creatinine is affected by muscle mass, diet, medicines, and acute change.
  • Does not determine CKD diagnosis, prognosis, monitoring, referral, or drug dose.

Frequently asked questions

Does this equation use race?

No. It is the 2021 race-free CKD-EPI creatinine equation.

Does eGFR below 60 always mean CKD?

CKD assessment includes persistence and other evidence; use current professional guidance.

Can I enter micromoles per liter?

Yes; the input converts to mg/dL.

Can I use it for a child?

No. This route is limited to adults.

Primary sources and evidence limits

Sources were checked 2026-10-05. A reference value, conversion, or schedule estimate is not a diagnosis, prescription, individualized treatment target, or substitute for professional care.

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